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Institute of Biomedical Ethics and History of Medicine (IBME)

New book chapter by Walter Glannon and Christian Ineichen on Philosophical Aspects of Closed-Loop-Neuroscience

Walter Glannon and Christian Ineichen have published a new book chapter, on Philosophical Aspects of Closed-Loop-Neuroscience in Closed Loop Neuroscience, Elsevier, 2016.

Abstract

Deep brain stimulation (DBS) uses mainly open-loop devices (OLDs) to modulate dysfunctional neural circuits in neurological and psychiatric disorders. Closed-loop devices (CLDs) are superior because they can automatically adjust themselves in response to changes in the brain and thus constantly monitor and correct adverse effects of electrical stimulation. Combining the feedback in closed-loop systems with electrophysiological and neurochemical recording will lead to “smart” DBS control that will maximize benefit and minimize harm for patients with these disorders. After weighing the benefits and risks of closed-loop devices, we consider their impact on perceptions of agency, autonomy, identity and the brain-mind relationship and whether there are significant differences between CLDs and OLDs in these respects.

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