Matthias  Eggel

Matthias Eggel

Post-Doctoral Researcher

matthias.eggel@ibme.uzh.ch

From 2006 to 2010, Matthias Eggel first did a bachelor in biology at the university of Zurich followed by a masters degree in human physiology. In his master thesis at the University Hospital Zurich, he investigated the effects of ionizing radiation and microtubuli-inhibitors on cancer.

From 2011 to 2015, he did PhD in molecular biology and biochemistry at the University of Berne investigating mechanisms of cell competition and their role in organ fitness, aging and cancer in Drosophila melanogaster.

From 2016 to 2018, Dr. Eggel pursued a PhD in biomedical ethics looking at better understanding the value-conflict between research and society in general and CRISR/CAS9 genome editing, specifically. 

Since 2019, Dr. Eggel is a Post-Doctoral Fellow at the institute for biomedical ethics and history of medicine.

Research interests

His research interests include:
•    Animal ethics: 
        Ethics of agriculture
        Ethics of veterinary practice
•    Animal research ethics: 
        Project evaluation in animal research (e.g. 3R, Harm-Benefit-Analysis)
        Ethical permissibility and scientific Validity of animal research (e.g. 3V)
        Conceptualization of Benefit in animal research
        Gene editing in animal research, e.g. genetic enhancement and disenhancement of research animals
        Regulatory Ethics in animal research

•    Human germline gene editing
 

Ongoing projects

Publications

Zora

Furmanova-Hollenstein P, Broggini-Tenzer A, Eggel M, Millard AL, Pruschy M. The microtubule stabilizer patupilone counteracts ionizing radiation-induced matrix metalloproteinase activity and tumor cell invasion. Radiation Oncology. 2013 Apr 30; 8:105.

Herwig Grimm* und Matthias Eggel*. White Paper and Colourful Language: Toward a Realistic View of Animal Research. ATLA 45, 1–3, 2017 *Authors contributed equally to this work.

Matthias Eggel* and Herwig Grimm*. The Road to Hell Is Paved with Good Intentions: Why Harm–Benefit Analysis and Its Emphasis on Practical Benefit Jeopardizes the Credibility of Research. Animals 2017 *Authors contributed equally to this work.

Matthias Eggel*, Anna Deplazes-Zemp, Herwig Grimm. Necessary, but not sufficient. The benefit concept in the project evaluation of animal research in context of the Directive 2010/63/EU, Animals 2018

Carolyn Neuhaus*, Matthias Eggel*, Herwig Grimm. Re-evaluating benefits in the moral justification of animal research: A comment on “Necessary Conditions for Morally Responsible Animal Research”. Cambridge quarterly of healthcare ethics. Accepted for publication. *Matthias Eggel and Carolyn P. Neuhaus contributed equally to this work.

Katrien Devolder*, Matthias Eggel*. No Pain, No Gain? In Defence of Genetically Disenhancing (Most) Research Animals. Animals 2019. *Authors contributed equally to this work.

Matthias Eggel and Rebecca Walker (2019). REPLACEMENT OR REDUCTION OF GENE-EDITED ANIMALS IN BIOMEDICAL RESEARCH: A COMPARATIVE ETHICS AND POLICY ANALYSIS. North Carolina Law Review

Springer, S., Dürnberger, C. & Eggel, M. Professional in food chains. Food ethics (2019) 3: 1. https://doi.org/10.1007/s41055-019-00043-7

Editing, reviewing and consulting activities

Reviewer for EURSAFE 2018 in Vienna;

Reviewer for Animals;

Editor of Special Issue of Food Ethics (2019)

Varia

Member of the Ethics Committee for Animal Experimentation (ECAE) of the Swiss Academy of Medical Sciences (SAMS) and the Swiss Academy of Sciences (SCNAT).

Reviewer for EURSAFE 2018 conference „Professionals in the food chain“ in Vienna

Editor of Special issue „Professionals in the food chain“ in the journal Food Ethics (2019)

Reviewer Laboratory Animals

Reviewer Animals