Genetic enhacenment and disenhancement of animals

Introduction

Millions of animals are used for scientific purposes in the EU every year. The procedures they undergo often cause significant pain, suffering and distress. New gene editing technologies now potentially offer a new and feasible way to genetically modify research animals in order to reduce or eliminate their ability to feel pain and to suffer. In this project, we analyze the ethical concerns this new technology and new possibility raise and evaluate the implications of such genetic modifications with regards to the legal regulations in animal research in Europe.

Keywords

Gene editing in animals, animal research ethics, enhancement

Management

Funding

Messerli Foundation

Project duration

2015 - 2018

Publications

Matthias Eggel and Rebecca Walker (2019). REPLACEMENT OR REDUCTION OF GENE-EDITED ANIMALS IN BIOMEDICAL RESEARCH: A COMPARATIVE ETHICS AND POLICY ANALYSIS. North Carolina Law Review

Katrien Devolder* and Matthias Eggel* (2019). No Pain, No Gain? In Defence of Genetically Disenhancing (Most) Research Animals. Animals, 9, 154